Gout is a metabolic disorder that primarily causes causes painful inflammation in the joints. Due to an increased concentration of uric acid in the blood - due to overproduction or reduced excretion - the uric acid can accumulate in the form of crystals in the joints, bursae, skin and organs (e.g. the kidneys). The joints in particular joints in particular can then become inflamed and typical symptoms such as pain restricted mobility, swelling and redness. The pain often begins pain often begins in the metatarsophalangeal joint.

The cause of the increased uric acid concentration can be congenital or acquired. Familial predisposition, obesity, certain eating habits and diseases such as diabetes or kidney problems play a role.